Shanzhiside methyl ester

SKU: orb1221921

Description

Shanzhiside methylester reduces neuropathic pain by activating spinal GLP-1 receptors and subsequently stimulating microglial β-endorphin expression via the p38 MAPK signaling.

Key Properties

• CAS Number: 64421-28-9
• MW: 406.38
• Purity: >98% (HPLC)
• Formula: C₁₇H₂₆O₁₁
• SMILES: [C@@H]1([C@H]2[C@@H](C(=CO1)C(=O)OC)[C@@H](C[C@]2(C)O)O)O[C@@H]1O[C@@H]([C@H]([C@@H]([C@H]1O)O)O)CO
• Target: DNA/RNA Synthesis
• Solubility: In Vitro: DMSO : 100 mg/mL (246.08 mM)

Bioactivity

• In Vivo:
  Shanzhiside methyl ester exerts dose-dependent and long-lasting (>4 h) anti-allodynic effects in spinal nerve injury-induced neuropathic rats, with a maximal inhibition of 49% and a projected ED50 of 40.4 μg.

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

DNA/RNA Synthesis