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Catalog Number | orb131734 |
---|---|
Category | Antibodies |
Description | Rabbit polyclonal to SH3RF1. E3 ubiquitin-protein ligase SH3RF1 belongs to the SH3RF family. SH3RF1 acts as a scaffold protein, contributes to Rac-induced signal transduction such as JNKs (MAPK8 and MAPK9) activation and induces apoptosis. Within a signaling complex, it probably recruits protein kinases such as MAP3K10 or MAP3K11 which are in turn activated leading to the sequential activation of MAP2K4, MAP2K7 and JNKs (MAPK8 and MAPK9). SH3RF1 may be involved in targeting of HIV-1 GAG and GAG-POL polyproteins to the plasma membrane. |
Species/Host | Rabbit |
Clonality | Polyclonal |
Tested applications | WB |
Reactivity | Human, Mouse |
Immunogen | C-terminal region of human SH3RF1 |
Concentration | 100 μg/ml BSA |
Dilution range | WB:1:1000-1:3000 |
Purity | Affinity purification |
Conjugation | Unconjugated |
MW | 93 |
UniProt ID | Q7Z6J0 |
Storage | -20°C |
Buffer/Preservatives | 0.01% NaN3 |
Alternative names | anti E3 ubiquitin-protein ligase SH3RF1 antibody, Read more... |
Note | For research use only |
Application notes | < strong>WB: The apparent protein size on WB may be different from the calculated M.W. due to modifications. < br>< strong>Experiment Notes: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the C-terminal region of human SH3RF1. |
Expiration Date | 12 months from date of receipt. |