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Catalog Number | orb1961318 |
---|---|
Category | Small Molecules |
Description | SGSH Protein, Human, Recombinant (His) |
Purity | 98.00% |
MW | 63 KDa, reducing conditions |
Biological Activity | N-Sulphoglucosamine Sulphohydrolase (SGSH) is an important member of the sulfatase family which is involved in the degradation of heparin sulfate. SGSH binds one calcium ion per subunit as a cofactor. SGSH catalyzes N-sulfo-D-glucosamine and H2O to D-glucosamine and sulfate. SGSH deficiency is result in mucopolysaccharidosis type 3A (MPS3A), a recessive lysosomal storage disease characterized by neurological dysfunction but relatively mild somatic manifestations. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
≥90% as determined by SDS-PAGE | |
This protein contains the human SGSH(Arg21-Leu502) was fused with the C-terminal His Tag and expressed in Mammalian cells. |
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