SEZ6 Protein, Human, Recombinant (His & Avi), Biotinylated

• Catalog Number: orb1959923
• Category: Proteins
• Description: Seizure-related protein 6 (Sez6) contributes to chronic pain development as sez6 knockout mice show attenuated pain behaviours after peripheral nerve injury, compared with control mice. The type I transmembrane isoform of Sez6 is cleaved by the β-amyloid precursor protein cleavage enzyme 1 (BACE1), resulting in Sez6 extracellular domain shedding from the neuron surface. SEZ6 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 100.7 kDa and the accession number is Q53EL9-1.
• Tag: C-His-Avi
• Purity: 98.00%
• MW: 100.7 kDa (predicted). Due to glycosylation, the protein migrates to 170-200 kDa based on Tris-Bis PAGE result.
• UniProt ID: Q53EL9
• Expression System: HEK293 Cells
• Biological Origin: Human
• Biological Activity: Seizure-related protein 6 (Sez6) contributes to chronic pain development as sez6 knockout mice show attenuated pain behaviours after peripheral nerve injury, compared with control mice. The type I transmembrane isoform of Sez6 is cleaved by the β-amyloid precursor protein cleavage enzyme 1 (BACE1), resulting in Sez6 extracellular domain shedding from the neuron surface. SEZ6 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 100.7 kDa and the accession number is Q53EL9-1.
• Expression Region: Leu20-His925
• Storage: -20°C
• Note: For research use only
• Expiration Date: 6 months from date of receipt.