SEMA4B Protein, Human, Recombinant (His)

Catalog Number: orb1960991

Catalog Number	orb1960991
Category	Proteins
Description	The class 4 semaphorins are integral membrane proteins that are widely expressed throughout the nervous system. SEMA4B is a single-pass type I membrane protein and contains one Ig-like C2-type (immunoglobulin-like) domain, one PSI domain and one Sema domain. Human SEMA4B is expressed in neurons. SEMA4B inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons. SEMA4B negatively regulates basophil-mediated Th2 and humoral memory responses.
Tag	C-6xHis
Purity	98.00%
MW	86 KDa (reducing condition)
UniProt ID	Q9NPR2
Protein Sequence	Leu39-Glu712
Expression System	HEK293 Cells
Biological Origin	Human
Biological Activity	The class 4 semaphorins are integral membrane proteins that are widely expressed throughout the nervous system. SEMA4B is a single-pass type I membrane protein and contains one Ig-like C2-type (immunoglobulin-like) domain, one PSI domain and one Sema domain. Human SEMA4B is expressed in neurons. SEMA4B inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons. SEMA4B negatively regulates basophil-mediated Th2 and humoral memory responses.
Expression Region	Leu39-Glu712
Storage	-20°C
Note	For research use only
Application notes	0
Expiration Date	6 months from date of receipt.

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Purity:	The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
MW:	The protein has a predicted molecular mass of 75.4 kDa after removal of the signal peptide. The apparent molecular mass of SEMA4B-His is approximately 70-100 kDa due to glycosylation.
Source:	Mammalian

Sizes Available: 100 μg, 10 μg, 50 μg