SCLY Protein, Human, Recombinant (His)

Catalog Number: orb1955963

Catalog Number	orb1955963
Category	Small Molecules
Description	SCLY Protein, Human, Recombinant (His)
Purity	98.00%
MW	49.63 kDa (predicted)
Biological Activity	SCLY, also known as selenocysteine lyase, belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. It is a novel enzyme that exclusively decomposes L-selenocysteine into L-alanine and H2Se in various mammalian tissues. SCLY contains pyridoxal 5'-phosphate and weighs approximately 85,000. SCLY participates in selenoamino acid metabolism. It employs one cofactor, pyridoxal phosphate. Its maximum reactivity is at about pH 9.0. It was shown that 1 mol of selenocysteine is converted to equimolar amounts of alanine and H2Se. The following amino acids are insert: L-cysteine, L-serine, L-cysteine sulfinate, selenocysteamine, Se-ethyl-DL-selenocysteine, and L-selenohomocysteine. L-Cysteine (Ki, 1.0 mM) competes with L-selenocysteine (Km, 0.83mM) to inhibit the enzyme reaction.
Note	For research use only
Expiration Date	12 months from date of receipt.

Purity:	≥90% as determined by SDS-PAGE
Source:	This protein contains the human SCLY(Met1-Ala445) was fused with the N-terminal His Tag and expressed in E. coli.