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Catalog Number | orb131863 |
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Category | Antibodies |
Description | Rabbit polyclonal to SATB2. DNA-binding protein SATB2 belongs to the CUT homeobox family. SATB2 binds to DNA, at nuclear matrix-or scaffold-associated regions. Furthermore, SATB2 is thought to recognize the sugarphosphate structure of double-stranded DNA. SATB2 is a transcription factor controlling nuclear gene expression, by binding to matrix attachment regions (MARs) of DNA and inducing a local chromatinloop remodeling. Also, SATB2 acts as a docking site for several chromatin remodeling enzymes and also by recruiting corepressors (HDACs) or coactivators (HATs) directly to promoters and enhancers. |
Species/Host | Rabbit |
Clonality | Polyclonal |
Tested applications | WB |
Reactivity | Human |
Immunogen | N-terminal region of human SATB2 |
Concentration | 100 μg/ml BSA |
Dilution range | WB:1:1000-1:3000 |
Purity | Affinity purification |
Conjugation | Unconjugated |
MW | 83 |
UniProt ID | Q9UPW6 |
Storage | -20°C |
Buffer/Preservatives | 0.01% NaN3 |
Alternative names | anti DNA-binding protein SATB2 antibody, anti Spec Read more... |
Note | For research use only |
Application notes | < strong>WB: The apparent protein size on WB may be different from the calculated M.W. due to modifications. < br>< strong>Experiment Notes: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the N-terminal region of human SATB2. |
Expiration Date | 12 months from date of receipt. |