Salicylic acid

SKU: orb1310417

Description

Salicylic acid, a natural phenolic compound derived from willow bark, acts as a cyclooxygenase (COX) inhibitor with anti-inflammatory properties. It is widely used in biochemical research to study inflammation pathways and prostaglandin biosynthesis in both in vitro and in vivo experimental models.

Research Area

Cell Biology, Immunology & Inflammation, Metabolism Research, Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 69-72-7
• MW: 138.12
• Purity: 95.61% (May vary between batches)
• Formula: C₇H₆O₃
• SMILES: OC(=O)C1=CC=CC=C1O
• Target: Apoptosis,Autophagy,Endogenous Metabolite,Mitophagy,COX
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (28.96 mM);H2O:1 mg/mL (7.24 mM);DMSO:141 mg/mL (1020.85 mM)

Bioactivity

• In Vivo:
  Although oral SA (5.5 mg/kg body weight) during the Hg(0) exposure did not reduce the Hg levels in these organs, it effectively counteracted the Hg(0)-induced growth inhibition, and improved the behavioral performance, accompanied by a series of ameliorations in the antioxidative defense and anti-inflammatory response.
• In Vitro:
  Salicylic acid (SA) is a phenolic phytohormone involved in plant defence against pathogens. It significantly stimulated PON1 activity in a concentration dependent manner.

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Autophagy, Apoptosis, 2-Hydroxybenzoic acid, Cyclooxygenase, COX, Endogenous Metabolite, EndogenousMetabolite, Mitophagy, Mitochondrial Autophagy, Inhibitor, inhibit, Salicylic acid

Compound Identifiers

PubChem CID

338