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Catalog Number | orb16641 |
---|---|
Category | Small Molecules |
Description | Salermide is an inhibitor of SIRT1 and SIRT2, causing tumor-specific apoptotic cell death. In MOLT4 leukemia cells, salermide causes 90% apoptosis within 72 hours (IC50 ~ 20 μM) by reactivating proapototic genes that are repressed by SIRT1. |
CAS Number | [1105698-15-4] |
MW | 394.47 |
SMILES | OC1=CC=C2C=CC=CC2=C1/C=N/C3=CC(NC(C(C)C4=CC=CC=C4)=O)=CC=C3 |
Formula | C26H22N2O2 |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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