SABA1

SKU: orb3032918

Description

SABA1 is an antibacterial agent effective against Pseudomonas aeruginosa and Escherichia coli. It works by inhibiting biotin carboxylase (BC), an enzyme that catalyzes the first step of the acetyl-CoA carboxylase (ACC) reaction, a process essential for bacterial fatty acid synthesis. What makes SABA1 particularly notable is its atypical inhibition mechanism: it binds to the biotin binding site of BC in the presence of ADP. This unique mode of action distinguishes SABA1 as a promising candidate for the development of new antibiotics, offering a potential solution to the growing challenge of antimicrobial resistance.

Key Properties

• CAS Number: 690681-65-3
• MW: 458.91
• Purity: 0.98
• Formula: C₂₂H₁₉ClN₂O₅S
• SMILES: CCOC(C1=CC=C(C=C1)NS(=O)(C2=CC(C(NC3=CC=CC=C3)=O)=CC=C2Cl)=O)=O

Storage & Handling

• Disclaimer: For research use only