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Catalog Number | orb1824343 |
---|---|
Category | Antibodies |
Description | Two families of retinoid receptors, RARs and RXRs, have been identified. Retinoic acid receptors (RARs) include RARa, RARb and RARg, each of which have a high affinity for all trans-retinoic acids and belong to the same class of nuclear transcription factors as thyroid hormone receptors, vitamin D3 receptor and ecdysone receptor. The ligand-binding domains of the RARs are highly conserved and RAR isoforms are expressed in distinct patterns throughout development and in the mature organism. Members of the retinoid X receptor (RXR) family, RXRa, RXRb and RXRg, are activated by 9-cis-RA, a stereo- and photo-isomer of all trans-RA that is expressed in vivo in both liver and kidney and may represent a widely used hormone. As is true for the RAR subfamily, the RXR receptors are closely related to each other both in their DNA-binding and ligand-binding domains and are encoded by separate genes at distinct chromosomal loci. |
Species/Host | Mouse |
Clonality | Monoclonal |
Clone Number | PCRP-RXRG-5C9 |
Tested applications | FACS |
Reactivity | Human |
Isotype | Mouse IgG2b |
Immunogen | Recombinant human RXR gamma protein was used as the immunogen for the RXRG antibody. |
Dilution range | Flow cytometry: 1-2ug/million cells |
Conjugation | Unconjugated |
Formula | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide |
Hazard Information | This RXR gamma antibody is available for research use only. |
UniProt ID | P78347 |
Storage | Aliquot the RXR gamma antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
ELISA, IF, IHC-P, WB | |
Human, Mouse | |
Rabbit | |
Polyclonal | |
Unconjugated |
IHC, WB | |
Human, Mouse, Rat | |
Rabbit | |
Polyclonal | |
Unconjugated |
IF, IH, WB | |
Human, Porcine, Primate | |
Rabbit | |
Polyclonal | |
Unconjugated |
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