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RSV-IN-1

SKU: orb1309146

Description

RSV-IN-1

Research Area

Infectious Disease & Virology

Images & Validation

Key Properties

CAS Number861139-16-4
MW427.48
Purity99.36%
FormulaC20H21N5O4S
SMILESCOc1ccc(cc1-c1nnc2c3ccccc3c(C)nn12)S(=O)(=O)N(C)CCO
TargetRSV
Solubility10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (9.36 mM);DMSO:125 mg/mL (292.41 mM)

Bioactivity

Target IC50
RSV (human):0.1 μM
In Vitro
The concentration of P13 that reduce the number of RSV plaques IC50 is 0.11 μM, in HEp-2 cells), with a CC50 of 310 μM for reducing HEp-2 cell viability, results in a Selective index (CC50 IC50 of 2818. These escape plaques are smaller and exhibit a non-syncytial phenotype compared to plaques formed withou the inhibitor.

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
DisclaimerFor research use only

Alternative Names

Respiratory syncytial virus, RSV IN 1, RSVIN1, RSV-IN-1, RSV, hRSV, inhibit, Inhibitor
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Key Properties

No computed properties available.

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Protocol Information

RSV-IN-1 (orb1309146)

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Step 1: Enter information below

(Recommended: An additional animal making an allowance for loss during the experiment)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

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1 mg
$ 140.00
5 mg
$ 270.00
1 ml x 10 mM (in DMSO)
$ 290.00
10 mg
$ 420.00
25 mg
$ 670.00
50 mg
$ 930.00
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