(R,S,S)-VH032

SKU: orb2300272

Description

(R,R,S)-VH032 is a VHL E3 ligase ligand used to construct PROTAC degraders, such as the tau-targeting molecule C004019. It disrupts the VHL/HIF-1α interaction and has been employed in both cellular and in vivo studies to develop targeted protein degradation therapies for neurodegenerative and oncological research.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2230826-33-0
• MW: 430.56
• Formula: C₂₂H₃₀N₄O₃S
• SMILES: C(NCC1=CC=C(C=C1)C=2SC=NC2C)(=O)[C@@H]3N(C([C@H](C(C)(C)C)N)=O)C[C@@H](O)C3
• Target: Ligand for E3 Ligase,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

135157027