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Catalog Number | orb1956114 |
---|---|
Category | Small Molecules |
Description | RPRD1B Protein, Human, Recombinant (His) |
Purity | 98.00% |
MW | Approxiamtely 39.3 kDa |
Biological Activity | RPRD1B, together with RPRD1A, can accompany RNAP II from promoter regions to 3'-untranslated regions during transcription in vivo, predominantly interact with phosphorylated RNAP II, and can reduce CTD S5- and S7-phosphorylated RNAP II at target gene promoters. RNA polymerase II C-terminal domain (CTD) phosphorylation is important for various transcription-related processes. RPRD1B is a transcriptional regulator that enhances expression of CCND1. It also enhances the transcription of a number of other cell cycle-related genes including CDK2, CDK4, CDK6 and cyclin-E but not CDKN1A, CDKN1B or cyclin-A. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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