Rocilinostat (ACY-1215)

• Catalog Number: orb180914
• Category: Small Molecules
• Description: Rocilinostat (ACY-1215) is a selective HDAC6 inhibitor with IC50 of 5 nM; > 10-fold more selective for HDAC6 than HDAC1/2/3 (class I HDACs) with slight activity against HDAC8, minimal activity against HDAC4/5/7/9/11, Sirtuin1, and Sirtuin2.
• CAS Number: [1316214-52-4]
• MW: 433.5
• SMILES: O=C(C1=CN=C(N(C2=CC=CC=C2)C3=CC=CC=C3)N=C1)NCCCCCCC(NO)=O
• Formula: C₂₄H₂₇N₅O₃
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

Chemical structure of Rocilinostat (ACY-1215)