RMC-9805

• Catalog Number: orb2653118
• Category: Small Molecules
• Description: RMC-9805 is a first-in-class, mutant-selective, covalent and orally bioavailable KRAS-G12D(ON) inhibitor. RMC-9805 exhibits direct anti-tumor effects and indirectly transformed the TME through inhibition of cancer cell-intrinsic KRAS-G12D oncogenic signaling.
• CAS Number: [2922732-54-3]
• MW: 1168.43754577637
• SMILES: FC(CN1C(C2=C([C@H](C)OC)N=CC(=C2)N2CCN(CC2)C2CC2)=C2CC(C)(C)COC([C@@H]3CCCN(C([C@H](C[C@H]4CN(C5=CC=C1C2=C5)CCO4)NC([C@H](C1CCCC1)N1CC[C@@]2(C1)CCN(C2)C([C@H]1[C@@H](C2CC2)N1C)=O)=O)=O)N3)=O)(F)F
• Formula: C₆₃H₈₈F₃N₁₁O₇
• Note: For research use only
• Expiration Date: 12 months from date of receipt.