RICTOR antibody

• Catalog Number: orb37672
• Category: Antibodies
• Description: Rabbit polyclonal antibody to RICTOR (Rapamycin insensitive companion of mTOR antibody) is also known as AVO3, PIA. It belongs to the pianissimo family. The Rictor-FRAP complex plays a role in PKC alpha phosphorylation, directly phosphorylates Akt/PKB on Ser473 in vitro and facilitates Thr308 phosphorylation by PDK1and it has also function as a drug target in tumors that have lost expression of PTEN, a tumor suppressor that opposes activation of Akt/PKB.
• Species/Host: Rabbit
• Clonality: Polyclonal
• Clone Number: RB14641
• Tested applications: IHC-P, WB
• Reactivity: Human, Mouse
• Isotype: Rabbit IgG
• Immunogen: Synthetic Peptide
• Dilution range: WB: 1:1000, IHC-P: 1:10-50
• Form/Appearance: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
• Conjugation: Unconjugated
• MW: 192218
• Target: RICTOR
• UniProt ID: Q6R327
• NCBI: NP_689969.2
• Alternative names: Anti-KIAA1999 antibody
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

Immunohistochemical analysis of formalin fixed and paraffin embedded human kidney tissue using RICTOR antibody