Refametinib (BAY86-9766)

• Catalog Number: orb251390
• Category: Small Molecules
• Description: Refametinib (RDEA119, Bay 86-9766) is a potent, ATP non-competitive and highly selective inhibitor of MEK1 and MEK2 with IC50 of 19 nM and 47 nM, respectively.
• CAS Number: [923032-37-5]
• MW: 572.34
• SMILES: O=S(C1(C[C@H](O)CO)CC1)(NC(C(NC(C(F)=C2)=CC=C2I)=C3F)=C(OC)C=C3F)=O
• Formula: C₁₉H₂₀F₃IN₂O₅S
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

Chemical structure of Refametinib (BAY86-9766)