TP63 Antibody

SKU: orb1410405

Description

Rabbit monoclonal antibody to p63 (Squamous, Basal & Myoepithelial Cell Marker)

Research Area

Cell Biology, Epigenetics & Chromatin, Stem Cell & Developmental Biology

Images & Validation

• Tested Applications: IHC
• Reactivity: Human

Key Properties

• Antibody Type: Recombinant Antibody
• Host: Rabbit
• Clonality: Monoclonal
• Isotype: IgG
• Clone No.: TP63/4379R
• Immunogen: Recombinant fragment (around aa600-680) of human TP63 protein (exact sequence is proprietary)
• Target: TP63
• Source/Expression System: HEK293 cells
• Molecular Weight: 63kDa
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: 200ug/ml of Ab purified by Protein A Column. Prepared in 10mM PBS with 0.05% rAlbumin & 0.05% azide. Also available WITHOUT rAlbumin & azide at 1.0mg/ml.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Amplified in squamous cell carcinoma (AIS); Chronic ulcerative stomatitis protein (CUSP); EEC3; Keratinocyte transcription factor KET; LMS; NBP; p40; P51/P63; p53 like transcription factor; p53-related protein p63; RHS; SHFM4; TAp63alpha; TP53CP; TP53L; TP63; TP73; TP73L; Transformation-related protein 63; Trp53rp1; Trp6;3

Analysis of Protein Array containing more than 19000 full-length human proteins using p63-Monospecific Recombinant Rabbit Monoclonal Antibody (TP63/4379R). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.

Formalin-fixed, paraffin-embedded human prostate cancer stained with p63 Recombinant Rabbit Monoclonal Antibody (TP63/4379R).

Formalin-fixed, paraffin-embedded human prostate cancer stained with p63 Recombinant Rabbit Monoclonal Antibody (TP63/4379R). HIER: Tris/EDTA, pH9.0, 45 min. 2°C: HRP-polymer, 30 min. DAB, 5 min.

Formalin-fixed, paraffin-embedded human prostate cancer stained with p63 Recombinant Rabbit Monoclonal Antibody (TP63/4379R). Inset: PBS instead of primary antibody, secondary antibody negative control.

Quick Database Links

Gene Symbol

TP63

UniProt

Q9H3D4