Recombinant MDM2 Antibody

• Catalog Number: orb2634995
• Category: Antibodies
• Description: MDM2 is a nuclear phosphoprotein that binds and inhibits transactivation by tumor protein p53. It can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. Overexpression of MDM2 can result in excessive inactivation of tumor protein p53, diminishing its tumor suppressor function. This protein also affects the cell cycle, apoptosis, and tumorigenesis through interactions with other proteins, including retinoblastoma 1 and ribosomal protein L5. Overexpression of MDM2 protein is detected in a variety of cancers.
• Clonality: Recombinant
• Species/Host: Rabbit
• Isotype: Rabbit IgG
• Conjugation: Unconjugated
• Reactivity: Human
• Immunogen: A portion of amino acids 126-254 was used as the immunogen for the recombinant MDM2 antibody.
• UniProt ID: Q00987
• Tested applications: ELISA
• Dilution range: ELISA (order BSA-free format for coating)
• Application notes: Optimal dilution of the recombinant MDM2 antibody should be determined by the researcher.
• Antibody Type: Primary Antibody
• Clone Number: MDM2/7061R
• Formula: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Hazard Information: This recombinant MDM2 antibody is available for research use only.
• Note: For research use only

SDS-PAGE analysis of purified, BSA-free recombinant MDM2 antibody (clone MDM2/7061R) as confirmation of integrity and purity.