Recombinant Human OSM

• Catalog Number: orb1921821
• Category: Proteins
• Description: Oncostatin M (OSM) is a multifunctional cytokine that belongs to the Interleukin-6 subfamily. Among the family members, OSM is most closely related to leukemia inhibitory factor (LIF) and it in fact utilizes the LIF receptor in addition to its specific receptor in the human. A biologically active OSM receptor has been previously described that consists of a heterodimer of leukemia inhibitory factor receptor (LIFR) and gp130. OSM is synthesized by stimulated T-cells and monocytes. The effects of OSM on endothelial cells suggest a pro-inflammatory role for OSM and endothelial cells possess a large number of OSM receptors. Recombinant human OSM has approximately 40% and 39% amino acid sequence identity with rat and murine OSM.
• Form/Appearance: Lyophilized Powder
• Purity: ≥95%
• MW: 25.8 kDa
• Entrez: 5008
• UniProt ID: P13725
• Source: CHO Cell
• Expression System: Eukaryotic cell
• Endotoxins: ≤10 EU/mg
• Storage: Use a manual defrost freezer and avoid repeated freeze - thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 month, 2 to 8°C under sterile conditions after reconstitution. 6 months, -20 to -70°C under sterile conditions after reconstitution.
• Alternative names: MGC20461; oncostatin M; oncostatin-M
• Note: For research use only
• Application notes: Application Notes: For research use only. Minimum Sample Size: 50μg/vial
• Expiration Date: 6 months from date of receipt.