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Recombinant Human OSM

Recombinant Human OSM

Catalog Number: orb1921821

DispatchUsually dispatched within 5-10 working days
$ 170.00
Catalog Numberorb1921821
CategoryProteins
DescriptionOncostatin M (OSM) is a multifunctional cytokine that belongs to the Interleukin-6 subfamily. Among the family members, OSM is most closely related to leukemia inhibitory factor (LIF) and it in fact utilizes the LIF receptor in addition to its specific receptor in the human. A biologically active OSM receptor has been previously described that consists of a heterodimer of leukemia inhibitory factor receptor (LIFR) and gp130. OSM is synthesized by stimulated T-cells and monocytes. The effects of OSM on endothelial cells suggest a pro-inflammatory role for OSM and endothelial cells possess a large number of OSM receptors. Recombinant human OSM has approximately 40% and 39% amino acid sequence identity with rat and murine OSM.
Form/AppearanceLyophilized Powder
Purity≥95%
MW25.8 kDa
Entrez5008
UniProt IDP13725
SourceCHO Cell
Expression SystemEukaryotic cell
Biological OriginHuman
Endotoxins≤10 EU/mg
StorageUse a manual defrost freezer and avoid repeated freeze - thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 month, 2 to 8°C under sterile conditions after reconstitution. 6 months, -20 to -70°C under sterile conditions after reconstitution.
Alternative namesMGC20461; oncostatin M; oncostatin-M
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NoteFor research use only
Application notesApplication Notes: For research use only. Minimum Sample Size: 50μg/vial
Expiration Date6 months from date of receipt.
  • Recombinant Human Oncostatin-M (OSM), partial (Active) [orb1785345]

    Greater than 95% as determined by SDS-PAGE.

    24.4 kDa

    Mammalian cell

    20 μg, 100 μg, 1 mg
  • Human ONCM protein (Active) [orb359147]

    > 97% as determined by SDS-PAGE and HPLC.

    22.0 kDa

    E.Coli

    100 μg, 500 μg, 10 μg
  • Human ONCM protein (Active) [orb359148]

    > 97% as determined by SDS-PAGE and HPLC.

    23.7 kDa

    E.Coli

    100 μg, 500 μg, 10 μg
  • Human ONCM protein (Active) [orb359149]

    > 95% as determined by SDS-PAGE and HPLC.

    25.8 kDa

    E.Coli

    10 μg, 100 μg, 500 μg
  • Human OSM protein [orb704586]

    Greater than 90% as determined by SDS-PAGE.

    38.2 kDa

    E.coli

    20 μg, 1 mg, 100 μg