RBMS2 Antibody / SCR3

SKU: orb2637050

Description

RBMS2 is a member of a small family of proteins that bind single stranded DNA or RNA. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, and are required for DNA binding. The RBMS proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. RBMS2 (RNA-binding motif, single-stranded-interacting protein 2) is a 407 amino acid protein that contains 2 RRM (RNA recognition motif) domains and localizes to nucleus. It has been suggested that RBMS2 suppresses Cdc2 kinase and Cdc13 cyclin mutants through the induction of translation of Cdc2. The RBMS2 gene is conserved in chimpanzee, canine, bovine, mouse, rat and zebrafish, and maps to human chromosome 12q13.3.

Images & Validation

• Tested Applications: ELISA, FACS, IP
• Dilution Range: ELISA (For coating, order BSA-free format),Immunoprecipitation: 1-2ug per 100-500ug of total protein (1ml of cell lysate),Flow cytometry: 1-2ug/million cells
• Reactivity: Human
• Application Notes:
  Optimal dilution of the RBMS2 antibody should be determined by the researcher.

Key Properties

• Antibody Type: Primary Antibody
• Host: Mouse
• Clonality: Monoclonal
• Isotype: Mouse IgG1
• Clone No.: PCRP-RBMS2-1B6
• Immunogen: Recombinant full-length human RBMS2 protein was used as the immunogen for the RBMS2 antibody.
• Purification: Protein A/G affinity
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: 1 mg/ml in 1X PBS; rAlbumin free, sodium azide free
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

UniProt

Q15434