Rat NAP-2 protein

• Catalog Number: orb107787
• Category: Proteins
• Description: Neutrophil Activating Peptide 2 (NAP-2) is proteolytically processed carboxyl-terminal fragments of platelet basic protein (PBP)which is found in the alpha-granules of human platelets. NAP-2 is a member of the CXC chemokines. Similar to other ELRdomain containing CXC chemokines such as IL-8 and the GRO proteins, NAP-2 has been shown to bind CXCR-2 and tochemoattract and activate neutrophils. Although CTAP-III, C-TG and PBP represent amino-terminal extended variants of NAP-2and possess the same CXC chemokine domains, these proteins do not exhibit NAP-2 activity. Recently, it has been shown thatthe additional amino-terminal residues of CTAP-III masks the critical ELR receptor binding domain that is exposed on NAP-2and may account for lack of NAP-2 activity.
• Tested applications: HPLC, SDS-PAGE
• Purity: > 97% by SDS-PAGE and HPLC analyses
• Conjugation: Unconjugated
• MW: 6.8 kDa
• Target: NAP-2
• Protein Sequence: IELRCRCTNT LSGIPLNSIS RVNVFRPGAH CDNVEVIATL KNGKEVCLDP TAPMIKKIVK KI
• Storage: Store at 4°C for up to two weeks. For long term storage, aliquot and store at -20°C, avoid freeze/thaw cycles.
• Buffer/Preservatives: Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4.
• Alternative names: Rat NAP-2/CXCL7 protein
• Note: For research use only
• Expiration Date: 6 months from date of receipt.

SDS-PAGE analysis of Rat NAP-2 protein