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Catalog Number | orb107782 |
---|---|
Category | Proteins |
Description | Recombinant Rat Macrophage-Derived Chemokine/CCL22. CCL22 is a protein encoded by the CCL22 gene. It is highly expressed in macrophage, monocyte-derived dendritic cell and thymus, additionally, also detected in the tissues of thymus, lymph node and appendix. CCL22 can bind to CCR4, and is a chemoattractant for monocytes, monocyte-derived dendritic cells, and natural killer cells, but not for neutrophils, eosinophils, and resting T-lymphocytes. After secreted from monocyte-derived dendritic cells, the protein can be proteolytic cleaved into three forms: MDC (3-69), MDC (5-69), MDC (7-69). |
Tested applications | HPLC, SDS-PAGE |
Reactivity | Rat |
Purity | > 96% by SDS-PAGE and HPLC analyses |
Conjugation | Unconjugated |
MW | 7.9 kDa |
Target | CCL22/MDC |
Protein Sequence | GPYGANVEDS ICCQDYIRHP LPPRFVKEFY WTSKSCRKPG VVLITIKNRD ICADPRMLWVKKILHKLA |
Source | E.coli |
Biological Activity | Fully biologically active when compared to standard. The biologically active determined by a chemotaxis bioassay using human T-lymphocytes is in a concentration range of 10-100 ng/ml. |
Endotoxins | Less than 1 EU/μg of rRtMDC/CCL22 as determined by LAL method. |
Storage | Store at 4°C for up to two weeks. For long term storage, aliquot and store at -20°C, avoid freeze/thaw cycles. |
Buffer/Preservatives | Lyophilized from a 0.2 μm filtered concentrated solution in 2xPBS, pH7.4 |
Alternative names | A 152E5.1 protein, ABCD 1 protein, C C motif chemo Read more... |
Note | For research use only |
Expiration Date | 6 months from date of receipt. |
SDS-PAGE analysis of Rat CCL22 protein
Rat | |
23.4-1500pg/mL | |
8.45pg/mL |
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