Rap1B C protein

• Catalog Number: orb533574
• Category: Proteins
• Description: Rap (Ras-proximate) proteins are GTPases that belong to the Ras superfamily of small GTP binding proteins. Rap1B is known to antagonize the mitotic and transforming activity of Ras. Rap1B can be activated by cAMP known to either stimulate or inhibit cell proliferation. The deletion of 17 C-terminal amino acids in Rap1B ΔC leads to the loss of the phosphorylation site Ser179 and the geranyl-geranylation site. Protein preparation is 53% GDP-and 47% GTP-loaded, measured by HPLC.
• Clonality: Recombinant
• Form/Appearance: liquid (Supplied in 64 mM Tris-HCl pH 7.0, 5 mM DTE, 400 mM NaCl, 10 mM MgCl 2and 0.1 mM GDP)
• Purity: > 90% (SDS-PAGE)
• MW: Theoretical MW: 19.0 kDa (167 amino acids)
• Source: E. coli
• Storage: store at -80 °C
• Note: For research use only
• Expiration Date: 6 months from date of receipt.