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Catalog Number | orb1960179 |
---|---|
Category | Small Molecules |
Description | RANK/TNFRSF11A Protein, Mouse, Recombinant (hFc) |
Purity | 98.00% |
MW | The protein has a predicted MW of 47.0 kDa. Due to glycosylation, the protein migrates to 57-67 kDa based on Tris-Bis PAGE result. |
Biological Activity | TNFRSF11A, also known as receptor activator of NF-κB (RANK), activates several signaling pathways, such as NF-κB, JNK, ERK, p38α, and Akt/PKB. RANK/TNFRSF11A is a novel and frequent target for de novo methylation in gliomas, which affects apoptotic activity and focus formation thereby contributing to the molecular pathogenesis of gliomas. RANK/TNFRSF11A Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 47.0 kDa and the accession number is O35305. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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