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Catalog Number | orb533598 |
---|---|
Category | Proteins |
Description | Raf is a member of the serine/threonine proteine kinase family involved in regulation of cell growth and differentiation and is the most important effector of Ras. Full-length Raf is composed of three conserved regions responsible for interaction with Ras, for phos-phorylation and for catalytic activity. RafRBD (Ras binding domain, amino acids 50-132) mediates interaction with membrane-anchored Ras necessary for activation of the kinase activity of Raf. The GST-Tag facilitates the protein‘s application in typical GST pull-down assays. The protein is GST-tagged on its N-terminus. There is a 7 AA linker between GST and RBD. |
Clonality | Recombinant |
Form/Appearance | liquid (Supplied in PBS, pH 7.4) |
Purity | > 90% (SDS-PAGE) |
MW | Theoretical MW: 42 kDa |
Source | E. coli |
Storage | store at -80 °C |
Note | For research use only |
Expiration Date | 6 months from date of receipt. |
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