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Catalog Number | orb746539 |
---|---|
Category | Small Molecules |
Description | RA-9 is a potent and selective proteasome-associated deubiquitinating enzymes (DUBs) inhibitor with favorable toxicity profile and anticancer activity. RA-9 blocks ubiquitin-dependent protein degradation without impacting 20S proteasome proteolytic activity. RA-9 selectively induces onset of apoptosis in ovarian cancer cell lines and primary cultures derived from donors. RA-9 induces endoplasmic reticulum (ER)-stress responses in ovarian cancer cells[1]. |
CAS Number | [919091-63-7] |
MW | 365.339504480362 |
SMILES | C(/C1C=CC([N+](=O)[O-])=CC=1)=C1/CNC/C(=C\C2C=CC([N+](=O)[O-])=CC=2)/C/1=O |
Formula | C19H15N3O5 |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
98.15% | |
919091-63-7 | |
365.34 | |
C19H15N3O5 |