(R)-3-Hydroxy Midostaurin

SKU: orb1990801

Description

(R)-3-Hydroxy Midostaurin is a major, pharmacologically active metabolite of midostaurin generated by CYP3A4 metabolism. This potent kinase inhibitor is utilized in biochemical and cellular research, particularly in studies investigating targeted therapies for acute myeloid leukemia (AML) in both in vitro and preclinical models.

Research Area

Cardiovascular Research, Metabolism Research, Signal Transduction

Key Properties

• CAS Number: 155848-20-7
• MW: 586.648
• Formula: C₃₅H₃₀N₄O₅
• SMILES: CO[C@@H]1[C@@H](C[C@@H]2O[C@]1(C)n1c3ccccc3c3c4[C@@H](O)NC(=O)c4c4c5ccccc5n2c4c13)N(C)C(=O)c1ccccc1
• Target: Others,Drug Metabolite,FLT

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

168011933