R-268712

• Catalog Number: orb304083
• Category: Small Molecules
• Description: Potent and selective inhibitor of the TGF-β type I receptor/ALK5 (IC50 = 2.5 nM). Exhibits ~ 5000-fold selectivity over p38 MAPK. Suppresses development of renal fibrosis in a unilateral ureteral obstruction model. Also reduces proteinuria, glomeruloscler
• CAS Number: [879487-87-3]
• MW: 363.39
• SMILES: FC1C=CC(C2C(C3N=C(C)C=CC=3)=NNC=2)=CC=1C1C=NN(CCO)C=1
• Formula: C₂₀H₁₈FN₅O
• Note: For research use only
• Expiration Date: 12 months from date of receipt.