QKI (pan) antibody

• Catalog Number: orb150962
• Category: Antibodies
• Description: Mouse monoclonal to QKI (RPE). QKI is also called Protein Quaking or HqkI. QKI is an RNA-binding protein that plays a central role in myelinization. QKI acts by regulating pre-mRNA splicing, mRNA export, mRNA stability and protein translation, and is itself, regulated by alternative splicing. QKI is expressed in the frontal cortex of brain, but is shown to be down-regulated in the brain of schizophrenic patients..
• Species/Host: Mouse
• Clonality: Monoclonal
• Clone Number: S147-6
• Tested applications: ICC, IHC, WB
• Reactivity: Human, Mouse, Rat
• Isotype: IgG2b
• Immunogen: Fusion protein amino acids 1-341 (full-length) of human QKI-5. Mouse: 100% identity (341/341 amino acids identical). Rat: 99% identity (339/341 amino acids identical) > 90% identity with QKI-6, QKI-7 and QKI-7b.
• Concentration: 1 mg/ml
• Dilution range: WB (1:1000)
• Conjugation: RPE
• MW: 36-38kDa
• Target: QKI
• Entrez: 9444
• UniProt ID: Q96PU8
• NCBI: NP_006766.1
• Storage: Conjugated antibodies should be stored at 4°C
• Buffer/Preservatives: PBS pH 7.4, 50% glycerol, 0.1% sodium azide *Storage buffer may change when conjugated
• Alternative names: Protein quaking antibody, Hqk antibody, HqkI antib
• Note: For research use only
• Application notes: 1 µg/ml of SMC-467 was sufficient for detection of Pan-QKI in 20 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
• Expiration Date: 12 months from date of receipt.