Pulrodemstat

SKU: orb2279579

Description

Pulrodemstat (CC-90011) is a potent, selective, reversible and orally active inhibitor of lysine specific demethylase-1 (LSD1) with an IC50 of 0.25 nM. Pulrodemstat is less enzymatic inhibition against LSD2, MOA-A, and MAO-B. Pulrodemstat induces acute myeloid leukemia (AML) and small cell lung cancer (SCLC) cells differentiation and has potent anticancer activity.

Key Properties

• CAS Number: 1821307-10-1
• MW: 451.47
• Purity: 0.98
• Formula: C₂₄H₂₃F₂N₅O₂
• SMILES: O(C1C=CC(C2=C(C3=CC(F)=C(C#N)C=C3)N=C(N3CCC(N)CC3)N(C)C2=O)=CC=1F)C

Storage & Handling

• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only