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Catalog Number | orb1961799 |
---|---|
Category | Proteins |
Description | Protein-Tyrosine Phosphatase 1C (PTP1C) belongs to the protein-tyrosine phosphatase family.which is known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. PTP1C is highly expressed in leukocyte cell type. It contains two SH2 domains and one tyrosine-protein phosphatase domain. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. In addition, PTP1C also modulates signaling by tyrosine phosphorylated cell surface receptors. |
Tag | C-6xHis |
Purity | 98.00% |
MW | 34 KDa (reducing condition) |
UniProt ID | P29350 |
Protein Sequence | Lys243-Ile541 |
Expression System | E. coli |
Biological Origin | Human |
Biological Activity | Protein-Tyrosine Phosphatase 1C (PTP1C) belongs to the protein-tyrosine phosphatase family.which is known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. PTP1C is highly expressed in leukocyte cell type. It contains two SH2 domains and one tyrosine-protein phosphatase domain. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. In addition, PTP1C also modulates signaling by tyrosine phosphorylated cell surface receptors. |
Expression Region | Lys243-Ile541 |
Storage | -20°C |
Note | For research use only |
Expiration Date | 6 months from date of receipt. |
≥90% as determined by SDS-PAGE | |
This protein contains the human PTPN6(Lys243-Ile541) was fused with the C-terminal His Tag and expressed in E. coli. |