PTK7/CCK4 Protein, Cynomolgus, Recombinant (His)

• Catalog Number: orb1960377
• Category: Proteins
• Description: Protein Tyrosine Kinase 7 (PTK7) is as a critical regulator of canonical and non-canonical Wnt-signaling during embryonic development and cancer cell formation. Disrupting PTK7 activity perturbs vertebrate nervous system development, and also promotes human cancer formation. Observations in different model systems suggest a complex cross-talk between PTK7 protein and Wnt signaling. PTK7/CCK4 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 75.73 kDa and the accession number is A0A2K5VNI5.
• Tag: C-His
• Purity: 98.00%
• MW: 75.73 kDa (predicted). Due to glycosylation, the protein migrates to 90-110 kDa based on Tris-Bis PAGE result.
• UniProt ID: A0A2K5VNI5
• Expression System: HEK293 Cells
• Biological Origin: Cynomolgus
• Biological Activity: Protein Tyrosine Kinase 7 (PTK7) is as a critical regulator of canonical and non-canonical Wnt-signaling during embryonic development and cancer cell formation. Disrupting PTK7 activity perturbs vertebrate nervous system development, and also promotes human cancer formation. Observations in different model systems suggest a complex cross-talk between PTK7 protein and Wnt signaling. PTK7/CCK4 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 75.73 kDa and the accession number is A0A2K5VNI5.
• Expression Region: Ala39-Thr712
• Storage: -20°C
• Note: For research use only
• Application notes: Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
• Expiration Date: 6 months from date of receipt.