PTBP1 Recombinant Antibody [8A1]

• Catalog Number: orb1995080
• Category: Antibodies
• Description: PTBP1 Recombinant Antibody [8A1]
• Clonality: Recombinant
• Tested applications: ELISA, IHC, WB
• Immunogen: A synthesized peptide derived from human PTBP1
• Form/Appearance: Liquid
• Conjugation: Unconjugated
• Storage: -20°C or -80°C
• Buffer/Preservatives: Liquid
• Alternative names: 57 kDa RNA-binding protein PPTB-1;heterogeneous nu
• Note: For research use only
• Application notes: Dilution Info: Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Activates exon skipping of its own pre-mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA. Represses the splicing of MAPT/Tau exon 10 (PubMed:15009664). In case of infection by picornaviruses, binds to the viral internal ribosome entry site (IRES) and stimulates the IRES-mediated translation (PubMed:21518806).
• Expiration Date: 12 months from date of receipt.