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Catalog Number | orb1961681 |
---|---|
Category | Small Molecules |
Description | PSGL-1/CD162 Protein, Mouse, Recombinant (aa 42-307, hFc) |
Purity | 98.00% |
MW | 90 KDa, reducing conditions |
Biological Activity | P-selectin glycoprotein ligand 1 is the high affinitycounter-receptor for P-selectin on expressed on activated endothelial cells and platelets. As such, it plays a critical role in the tethering of these cells to activated platelets or endothelia expressing P-selectin. As cell adhesion molecules, multiple studies have shown that PSGL-1/ P-selectin interaction is required for the normal recruitment of leukocytes during inflammatory reactions, and also participates in hemostatic responses. PSGL-1 can also bind to other two members of the selectin family, E-selectin (endothelial) and L-selectin (leukocyte), but binds best to P-selectin. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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