PRPS1 Antibody

• Catalog Number: orb1263502
• Category: Antibodies
• Description: PRPS1 Antibody
• Species/Host: Rabbit
• Clonality: Polyclonal
• Tested applications: WB
• Predicted Reactivity: Bovine, Monkey, Rat, Xenopus
• Reactivity: Human, Mouse
• Isotype: Rabbit Ig
• Immunogen: This PRPS1/PRPS2/PRPS3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 79-109 amino acids from the N-terminal region of human PRPS1/PRPS2/PRPS3.
• Concentration: batch dependent
• Dilution range: For WB starting dilution is: 1:1000
• Form/Appearance: Liquid
• Conjugation: Unconjugated
• MW: 35 kDa
• Target: PRPS1
• UniProt ID: P60891
• NCBI: P60891
• Storage: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Buffer/Preservatives: Supplied in PBS with 0.09% (W/V) sodium azide.
• Alternative names: Ribose-phosphate pyrophosphokinase 1, PPRibP, Phos
• Note: For research use only
• Application notes: For WB starting dilution is: 1:1000
• Expiration Date: 12 months from date of receipt.

Antibody is used in Western blot to detect PRPS1/2/3 in mouse kidney tissue lysate (Lane 1) and Hela cell lysate (Lane 2).

Role of PPP during MSC transformation. (A) G6PD activity decreased during MSC transformation. Western blot confirms the down-regulation of G6PD and the up-regulation of PRPS at the late stages of transformation.