PROTAC ER Degrader-14

SKU: orb2945534

Description

PROTAC ER Degrader-14 (compound 86) is a heterobifunctional degrader that recruits the estrogen receptor (ER) to the CRBN E3 ligase for ubiquitination and proteasomal degradation. This tool compound is used in research to study ER biology and targeted protein degradation in both cellular and in vivo models.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2504911-73-1
• MW: 743.865
• Formula: C₄₄H₄₆FN₅O₅
• SMILES: FC=1C=C([C@H]2[C@H](COC=3C2=CC=C(O)C3)C4=CC=CC=C4)C=CC1N5CCC(CN6CCN(CC6)C=7C=C8C(=CC7)C(=O)N(C8)[C@@H]9C(=O)NC(=O)CC9)CC5
• Target: PROTACs,Estrogen Receptor/ERR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

155172545