VHL Ligand 35

SKU: orb3210754

Description

VHL ligand 35 (Compound 14) is a ligand for the von Hippel-Lindau protein (pVHL) E3 ubiquitin ligase, with a dissociation constant (Kd) of 0.291 μM. It disrupts the protein-protein interaction between pVHL and hypoxia-inducible factor 1α (HIF-1α).

Key Properties

• CAS Number: 1631137-31-9
• MW: 619.77
• Formula: C₃₃H₄₁N₅O₅S
• SMILES: C([C@@H](NC([C@H](CC1=CC=CC=C1)NC(C)=O)=O)C(C)(C)C)(=O)N2[C@H](C(NCC3=CC=C(C=C3)C4=C(C)N=CS4)=O)C[C@@H](O)C2
• Target: Ligands for E3 Ligase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Ligands for E3 Ligase