Tris(3-hydroxypropyltriazolylmethyl)amine

SKU: orb2941092

Description

Tris(3-hydroxypropyltriazolylmethyl)amine (THPTA) serves as an effective accelerator ligand for copper-catalysed azide-alkyne coupling (CuAAC), concurrently reducing toxicity to cells or organisms.

Research Area

Signal Transduction

Key Properties

• CAS Number: 760952-88-3
• MW: 434.5
• Purity: 99.48% (May vary between batches)
• Formula: C₁₈H₃₀N₁₀O₃
• SMILES: OCCCN1N=NC(CN(CC2=CN(CCCO)N=N2)CC3=CN(CCCO)N=N3)=C1
• Target: Others
• Solubility: DMSO:80 mg/mL (184.12 mM);H2O:≥ 130 mg/mL

Bioactivity

• In Vitro:
  Tris(3-hydroxypropyltriazolylmethyl)amine (250 μM, 1-5 minutes) as a ligand to accelerate the CuAAC reaction significantly improved the rate and efficiency of the CuAAC reaction, while protecting cells from oxidative damage.
  Read more...

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

THPTA

Compound Identifiers

PubChem CID

85325313