Theophylline

SKU: orb1309828

Description

Theophylline (1,3-Dimethylxanthine) is a natural methylxanthine found in tea that acts as a non-selective phosphodiesterase inhibitor, elevating intracellular cAMP levels. This mechanism underpins its research applications in studying bronchial relaxation, cardiac stimulation, and inflammatory pathways in both cellular and animal models.

Research Area

Cell Biology, Epigenetics & Chromatin, Immunology & Inflammation, Metabolism Research, Molecular Biology, Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 58-55-9
• MW: 180.164
• Purity: 99.98% (May vary between batches)
• Formula: C₇H₈N₄O₂
• SMILES: CN1C2=C(NC=N2)C(=O)N(C)C1=O
• Target: HDAC,PDE,Apoptosis,Autophagy,TNF,Adenosine Receptor,Interleukin,Endogenous Metabolite
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (5.55 mM);DMSO:16.83 mg/mL (93.42 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

chronic obstructive pulmonary disease, Endogenous Metabolite, Autophagy, asthma, 1,3-Dimethylxanthine, airway smooth muscle, Adenosine Receptor, Adenosine receptor, AdenosineReceptor, A549 cells, HDAC2, Inhibitor, EndogenousMetabolite, eosinophils, PDE, NF-κB, inhibit, I-κBα, P1 receptor, Theophylline, Theo 24, Theo24, Theo-24, Phosphodiesterase (PDE), phosphodiesterase

Compound Identifiers

PubChem CID

2153