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Thalidomide-5-(PEG2-amine)

SKU: orb3028295

Description

Thalidomide-5-(PEG2-amine) is a Thalidomide analogue that includes an E3 ligase ligand substituted with a terminal amine group. The amine group can react with NHS esters or carboxylic acids in the presence of EDC or HATU. The PEG spacer enhances water solubility.

Research Area

Metabolism Research; Pharmacology & Drug Discovery, Pharmacology & Drug Discovery

Images & Validation

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Key Properties

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CAS Number2550398-08-6
MW432.427
FormulaC20H24N4O7
SMILESO=C(NCCOCCOCCN)C1=CC=C2C(=O)N(C(=O)C2=C1)C3C(=O)NC(=O)CC3
TargetE3 Ligase Ligand-Linker Conjugates

Storage & Handling

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Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information