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Thalidomide-5-CH2-NH2 hydrochloride

SKU: orb1909106

Description

Thalidomide-5-CH2-NH2 (hydrochloride) is a cereblon (CRBN)-binding ligand used to construct PROTAC degraders. This small molecule enables targeted protein degradation and is a key tool for probing protein function in both cellular and in vivo disease models.

Research Area

Cell Biology, Pharmacology & Drug Discovery

Images & Validation

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Key Properties

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CAS Number1010100-22-7
MW323.732
FormulaC14H14ClN3O4
SMILESO=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC(CN)=C3)=O.[H]Cl
TargetE3 Ligase Ligand-Linker Conjugates,Others,Apoptosis,Autophagy

Storage & Handling

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Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

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No computed properties available.

Protocol Information