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Sennoside

SKU: orb3179496

Description

Sennoside is an orally active anthraquinone glycoside used as a stimulant laxative. It enhances gastrointestinal motility and secretion by activating 5-HT4 receptors in the myenteric plexus and inhibiting Na+/K+-ATPase activity. Sennoside is considered promising for research in chronic constipation.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number517-43-1
MW862.75
FormulaC42H38O20
SMILESO=C(O)C1=CC(O)=C2C(=O)C=3C(OC4OC(CO)C(O)C(O)C4O)=CC=CC3C(C2=C1)C5C=6C=CC=C(OC7OC(CO)C(O)C(O)C7O)C6C(=O)C8=C(O)C=C(C=C85)C(=O)O
TargetATPase,5-HT Receptor

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information