SCD1 inhibitor-3

SKU: orb1691844

Description

SCD1 inhibitor-3

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1282606-48-7
• MW: 393.37
• Purity: 99.50% (May vary between batches)
• Formula: C₁₉H₁₆FN₇O₂
• SMILES: Fc1ccc(Cn2ncn(-c3cc(n[nH]3)C(=O)NCc3cccnc3)c2=O)cc1
• Target: Dehydrogenase,Stearoyl-CoA Desaturase (SCD)
• Solubility: DMSO:35 mg/mL (88.97 mM)

Bioactivity

• In Vivo:
  SCD1 inhibitor-3 (compound 17a), administered orally at a dosage of 5 mg/kg for 4 hours, effectively decreases the plasma C16:1/C16:0 triglycerides desaturation index by 54% in Lewis rats . Furthermore, a dose-responsive reduction in the plasma triglycerides desaturation index is observed when the dosage ranges from 2 to 10 mg/kg, under the same conditions, indicating a dose-dependent efficacy .
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

SCD1, SCD1-IN-3, SCD1 inhibitor 17a, SCD1 inhibitor-3

Compound Identifiers

PubChem CID

51354459