S107 hydrochloride

SKU: orb1704791

Description

S107 hydrochloride is a RyR-selective 1,4-benzothiazepine derivative that stabilizes the RyR2 channel by increasing the binding affinity of calstabin2. This action is particularly relevant for studying mutant or PKA-phosphorylated channels in cardiovascular research, with applications in both in vitro and in vivo models of conditions like catecholaminergic polymorphic ventricular tachycardia (CPVT).

Key Properties

• CAS Number: 1357476-46-0
• MW: 245.77
• Formula: C₁₁H₁₆ClNOS
• SMILES: Cl.COc1ccc2SCCN(C)Cc2c1
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

53311704