Radezolid

SKU: orb1307814

Description

Radezolid

Research Area

Infectious Disease & Virology

Key Properties

• CAS Number: 869884-78-6
• MW: 438.45
• Purity: 98.06% (May vary between batches)
• Formula: C₂₂H₂₃FN₆O₃
• SMILES: CC(=O)NC[C@H]1CN(C(=O)O1)c1ccc(c(F)c1)-c1ccc(CNCc2cnn[nH]2)cc1
• Target: Antibiotic,Antibacterial
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.56 mM);DMSO:35.07 mg/mL (79.99 mM)

Bioactivity

• In Vitro:
  Radezolid consistently demonstrates superior potency to linezolid across all tested bacteria, maintaining this advantage regardless of the bacterium's sensitivity, when the concentration measurements are standardized to weight (mg/L). This is evidenced by Radezolid's MIC values, which are always equal to or lower than those of linezolid—by up to 3 log2 dilutions—for strains susceptible to linezolid, and exhibit an 8-fold potency increase against linezolid-resistant strains. Additionally, Radezolid, alongside TR-700, is effective against mutants with 3-copy alterations at G2447T, G2576T, and G2576T/T2571C positions .
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

inhibit, Inhibitor, Antibiotic, Bacterial, Radezolid, RX 1741, RX1741, RX-1741

Compound Identifiers

PubChem CID

11224409