PROTAC CCR9 Degrader 1

SKU: orb3211505

Description

PROTAC CCR9 Degrader 1 is a PROTAC-based degrader specifically targeting CCR9. It functions by recruiting the VHL E3 ligase, leading to the ubiquitination and proteasomal degradation of CCR9, thereby reducing its intracellular levels. The compound has a Ki value of 78.0 nM for human CCR9. Additionally, PROTAC CCR9 Degrader 1 modulates GPCR activity by binding to the allosteric site within CCR9 and is applicable in research related to Crohn's disease.

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Key Properties

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Target	CCR,PROTACs,E1/E2/E3 Enzyme

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Gene Symbol

CCR,PROTACs,E1/E2/E3 Enzyme

Protocol Information

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CAS Number:	2906191-39-5
MW:	618.10
Formula:	C₂₈H₃₂ClN₅O₇S

PROTAC CCR9 Degrader 1

Description

Images & Validation

Key Properties

Storage & Handling

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