PRE-084 hydrochloride

SKU: orb1304434

Description

PRE-084 hydrochloride is a potent and selective σ1 receptor agonist with an IC50 of 44 nM. It is widely used as a pharmacological tool in neuroscience research to investigate σ1 receptor function in both in vitro binding assays and in vivo behavioral models.

Research Area

Immunology & Inflammation, Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 75136-54-8
• MW: 353.88
• Purity: 99.61% (May vary between batches)
• Formula: C₁₉H₂₈ClNO₃
• SMILES: Cl.O=C(OCCN1CCOCC1)C1(CCCCC1)c1ccccc1
• Target: NO Synthase,Akt,Sigma receptor
• Solubility: DMSO:31 mg/mL (87.6 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.65 mM);H2O:35.4 mg/mL (100.03 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

cortical cells, ALS, Alzheimer's disease, Akt, neuroprotection, neurological diseases, Nitric oxide synthases, NO Synthase, inhibit, NOS, Inhibitor, σ1, Protein kinase B, Sigma Receptor, Sigmareceptor, Sigma receptor, PRE-084, PRE084 Hydrochloride, PRE084 hydrochloride, PRE-084 Hydrochloride, PRE 084, PRE 084 hydrochloride, PRE 084 Hydrochloride, PRE084, PKB

Compound Identifiers

PubChem CID

11314197