Pralmorelin

SKU: orb1219360

Description

Pralmorelin is an oral active synthetic peptide analogue of MEK. Pralmorelin is an auxin releasing peptide/growth hormone secretory receptor agonist, can selectively stimulate ghrelin receptor and cause growth hormone release, has shown anti-inflammatory activity.An anti-inflammatory role for ghrelin (GHRP-2) in PKC-mediated inflammation of granulosa cells, at least in part, due to its inhibitory effect on PKC-induced activation of p38, JNK and NF-κB, possibly by targeting to MKP-1 and PP2A.An insulin tolerance test (ITT), CRH stimulation test, and GHRP-2 test on 47 patients suspected of having a hypothalamo-pituitary disorder were preformed. The results indicate that the GHRP-2 test may induce ACTH secretion from the pituitary gland through direct stimulation.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 158861-67-7
• MW: 817.99
• Purity: >98% (HPLC)
• Formula: C₄₅H₅₅N₉O₆
• SMILES: NCCCC[C@@H](C(N)=O)NC([C@@H](CC1=CC=CC=C1)NC([C@H](CC2=CNC3=C2C=CC=C3)NC([C@H](C)NC([C@@H](CC4=CC=C5C=CC=CC5=C4)NC([C@@H](C)N)=O)=O)=O)=O)=O.[H]Cl.[H]Cl
• Target: GHSR

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

GHSR